WFDC2 Protein (AA 28-124) (Fc Tag)
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- Target See all WFDC2 Proteins
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-124
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Origin
- Dog
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This WFDC2 protein is labelled with Fc Tag.
- Purpose
- Canine HE4 Protein
- Sequence
- Gly28-Phe124
- Characteristics
- Recombinant Canine HE4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly28-Phe124.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- Alternative Name
- HE4 (WFDC2 Products)
- Synonyms
- WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein
- Background
- The ovarian cancer biomarker HE4 is known to promote proliferation, metastasis, chemoresistance, and suppression of cytotoxic lymphocytes. HE4 has the ability to affect signaling events and gene expression in multiple cell types of the tumor microenvironment, which could contribute to angiogenesis and altered immunogenic responses in ovarian cancer.
- Molecular Weight
- 37.06 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
- UniProt
- Q28894
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