GFRA3 Protein (AA 29-379) (His tag)
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- Target See all GFRA3 Proteins
- GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-379
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GFRA3 protein is labelled with His tag.
- Purpose
- Mouse GFRA3 Protein
- Sequence
- Asn29-Arg379
- Characteristics
- Recombinant Mouse GFRA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn29-Arg379.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Mouse GFRA3, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Mouse ARTN, hFc Tag with the EC50 of 0.12μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product GFRA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))
- Alternative Name
- GFRA3 (GFRA3 Products)
- Synonyms
- GFRA3 Protein, GFRalpha3 Protein, Y15110 Protein, GDNF family receptor alpha 3 Protein, glial cell line derived neurotrophic factor family receptor alpha 3 Protein, Gfra3 Protein, GFRA3 Protein
- Background
- GDNF (glial-cell-line derived neurotrophic factor) is a potent neurotrophic factor for dopaminergic neurons. Neuropsychiatric diseases and their treatments are associated with alterations in the levels of both GDNF and its receptor family (GDNF family receptor alpha or GFRA). GFRA1, GFRA2 and GFRA3 are located in chromosomal regions with suggestive linkage to schizophrenia.
- Molecular Weight
- 40.3 kDa. Due to glycosylation, the protein migrates to 47-52 kDa based on Tris-Bis PAGE result.
- UniProt
- O35118
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