GDF15 Protein (AA 189-303) (His tag)
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- Target See all GDF15 Proteins
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 189-303
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GDF15 protein is labelled with His tag.
- Purpose
- Rat GDF15 Protein
- Sequence
- Ser189-Ala303
- Characteristics
- Recombinant Rat GDF15 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ser189-Ala303.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Rat GDF15, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Mouse GFRAL, His Tag with the EC50 of 6.2μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product GDF15 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM HAc ( pH 2.9).
- Buffer
- Lyophilized from 0.22μm filtered solution in 50 mM HAc ( pH 2.9). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Alternative Name
- GDF15 (GDF15 Products)
- Synonyms
- GDF15 Protein, GDF-15 Protein, MIC-1 Protein, MIC1 Protein, NAG-1 Protein, PDF Protein, PLAB Protein, PTGFB Protein, SBF Protein, growth differentiation factor 15 Protein, GDF15 Protein, Gdf15 Protein
- Background
- Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
- Molecular Weight
- 13.68 kDa. The protein migrates to 15-17 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9Z0J6
- Pathways
- SARS-CoV-2 Protein Interactome
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