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FCRL2 Protein (AA 20-401) (His tag)

FCRL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274591
  • Target See all FCRL2 Proteins
    FCRL2 (Fc Receptor-Like 2 (FCRL2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-401
    Origin
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FCRL2 protein is labelled with His tag.
    Purpose
    Human FCRL2/IRTA4 Protein
    Sequence
    Leu20-Val401
    Characteristics
    Recombinant Human FCRL2/IRTA4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Val401.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human FCRL2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FCRL2 (Fc Receptor-Like 2 (FCRL2))
    Alternative Name
    FCRL2 (FCRL2 Products)
    Synonyms
    CD307b Protein, FCRH2 Protein, IFGP4 Protein, IRTA4 Protein, SPAP1 Protein, SPAP1A Protein, SPAP1B Protein, SPAP1C Protein, fcrh2 Protein, ifgp4 Protein, irta4 Protein, spap1 Protein, spap1a Protein, spap1b Protein, spap1c Protein, Fc receptor like 2 Protein, Fc receptor-like 2 Protein, Fc receptor-like protein 2 Protein, Fc receptor-like 2 L homeolog Protein, FCRL2 Protein, LOC612038 Protein, fcrl2.L Protein
    Background
    Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation, P < 0.0001) and cells of other hematological diseases.
    Molecular Weight
    42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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