EPH Receptor A10 Protein (EPHA10) (AA 23-565) (His tag)
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- Target See all EPH Receptor A10 (EPHA10) Proteins
- EPH Receptor A10 (EPHA10)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-565
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EPH Receptor A10 protein is labelled with His tag.
- Purpose
- Mouse EPHA10 Protein
- Sequence
- Leu23-Ala565
- Characteristics
- Recombinant Mouse EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Ala565.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EPHA10 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EPH Receptor A10 (EPHA10)
- Alternative Name
- EPHA10 (EPHA10 Products)
- Synonyms
- A330090H18 Protein, RGD1562679 Protein, EPH receptor A10 Protein, Eph receptor A10 Protein, EPHA10 Protein, Epha10 Protein
- Background
- EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer.
- Molecular Weight
- 59.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
- Pathways
- RTK Signaling
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