EPH Receptor B4 Protein (EPHB4) (AA 16-539) (His tag)
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- Target See all EPH Receptor B4 (EPHB4) Proteins
- EPH Receptor B4 (EPHB4)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-539
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EPH Receptor B4 protein is labelled with His tag.
- Purpose
- Human EphB4 Protein
- Sequence
- Leu16-Ala539
- Characteristics
- Recombinant Human EphB4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu16-Ala539.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EPH Receptor B4 (EPHB4)
- Alternative Name
- EphB4 (EPHB4 Products)
- Synonyms
- HTK Protein, MYK1 Protein, TYRO11 Protein, htk Protein, myk1 Protein, ephB4a Protein, tyro11 Protein, ephb4b Protein, MGC130997 Protein, AI042935 Protein, Htk Protein, MDK2 Protein, Myk1 Protein, Tyro11 Protein, cb646 Protein, ephB4 Protein, rtk5 Protein, EphB-rtk8 Protein, cb417 Protein, rtk8 Protein, EPH receptor B4 Protein, EPH receptor B4 L homeolog Protein, EPH receptor B4 S homeolog Protein, Eph receptor B4 Protein, eph receptor B4a Protein, eph receptor B4b Protein, EPHB4 Protein, ephb4.L Protein, ephb4.S Protein, ephb4 Protein, Ephb4 Protein, ephb4a Protein, ephb4b Protein
- Background
- The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest family of receptor tyrosine kinases (RTKs) that include two major subclasses, EphA and EphB. They form an important cell communication system with critical and diverse roles in a variety of biological processes during embryonic development. The emerging picture suggests that EphB4 is a valuable and attractive therapeutic target for upper aerodigestive malignancies.
- Molecular Weight
- 58.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_004435
- Pathways
- RTK Signaling
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