EGFR Protein (AA 25-647) (His tag)
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- Target See all EGFR Proteins
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-647
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EGFR protein is labelled with His tag.
- Purpose
- Mouse EGFR/HER1 Protein
- Sequence
- Leu25-Ser647
- Characteristics
- Recombinant Mouse EGFR/HER1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu25-Ser647.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EGFR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Alternative Name
- EGFR (EGFR Products)
- Synonyms
- C-erb Protein, CG10079 Protein, D-EGFR Protein, D-Egf Protein, DEGFR Protein, DER Protein, DER flb Protein, DER/EGFR Protein, DER/faint little ball Protein, DER/top Protein, DER/torpedo Protein, DER1 Protein, DEgfr Protein, Degfr Protein, Der Protein, DmHD-33 Protein, Dmel\\CG10079 Protein, EFG-R Protein, EGF-R Protein, EGFR Protein, EGFr Protein, EGfr Protein, EK2-6 Protein, Egf Protein, Egf-r Protein, EgfR Protein, El Protein, Elp Protein, Elp-1 Protein, Elp-B1 Protein, Elp-B1RB1 Protein, HD-33 Protein, TOP Protein, Torpedo/DER Protein, Torpedo/Egfr Protein, c-erbB Protein, d-egf-r Protein, dEGFR Protein, dEGFR1 Protein, dEgfr Protein, der Protein, egfr Protein, flb Protein, l(2)05351 Protein, l(2)09261 Protein, l(2)57DEFa Protein, l(2)57EFa Protein, l(2)57Ea Protein, mor1 Protein, top Protein, top/DER Protein, top/flb Protein, torpedo/Egfr Protein, torpedo/egfr Protein, EGFR12 Protein, EGFR15 Protein, egfr1 Protein, Erbb2 Protein, ERBB Protein, ERBB1 Protein, HER1 Protein, PIG61 Protein, mENA Protein, ErbB-1 Protein, Errp Protein, 9030024J15Rik Protein, AI552599 Protein, Erbb Protein, Errb1 Protein, Wa5 Protein, wa-2 Protein, wa2 Protein, epidermal growth factor receptor Protein, Epidermal growth factor receptor Protein, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Protein, EGFR Protein, Egfr Protein, egfra Protein, egfr1 Protein, LOC5564544 Protein
- Background
- The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
- Molecular Weight
- 70.40 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- UniProt
- Q01279
- Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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