DLL3 Protein (AA 27-477) (His tag)
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- Target See all DLL3 Proteins
- DLL3 (delta Like Protein 3 (DLL3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-477
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLL3 protein is labelled with His tag.
- Purpose
- Cynomolgus DLL3 Protein
- Sequence
- Ala27-Ala477
- Characteristics
- Recombinant Cynomolgus DLL3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Ala477.
- Purity
- > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by SEC-HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus DLL3, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product DLL3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 200 mM NaCl, 200 mM L-arginine ( pH 8.5).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DLL3 (delta Like Protein 3 (DLL3))
- Alternative Name
- DLL3 (DLL3 Products)
- Synonyms
- SCDO1 Protein, pu Protein, pudgy Protein, delta like canonical Notch ligand 3 Protein, delta-like 3 (Drosophila) Protein, DLL3 Protein, Dll3 Protein
- Background
- Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
- Molecular Weight
- 48.80 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WSR1
- Pathways
- Notch Signaling
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