DKK3 Protein (AA 23-350) (His-Avi Tag)
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- Target See all DKK3 products
- DKK3
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-350
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DKK3 protein is labelled with His-Avi Tag.
- Purpose
- Human DKK3 Protein
- Sequence
- Pro23-Ile350
- Characteristics
- Recombinant Human DKK3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Pro23-Ile350.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DKK3
- Abstract
- DKK3 Products
- Synonyms
- REIC Protein, RIG Protein, reic Protein, dkk-3 Protein, AW061014 Protein, C87148 Protein, Reic Protein, p29 Protein, dickkopf WNT signaling pathway inhibitor 3 Protein, dickkopf WNT signaling pathway inhibitor 3 S homeolog Protein, DKK3 Protein, dkk3 Protein, dkk3.S Protein, Dkk3 Protein
- Background
- Dkk-3, also known as REIC (Reduced Expansion in Immortalized Cells), is one of four numbered members of the Dickkopf family of Wnt antagonists.DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
- Molecular Weight
- 39.5 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9UBP4
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