DDR2 Protein (AA 22-399) (His tag)
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- Target See all DDR2 Proteins
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-399
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DDR2 protein is labelled with His tag.
- Purpose
- Human DDR2 Protein
- Sequence
- Lys22-Arg399
- Characteristics
- Recombinant Human DDR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys22-Arg399.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Alternative Name
- DDR2 (DDR2 Products)
- Synonyms
- MIG20a Protein, NTRKR3 Protein, TKT Protein, TYRO10 Protein, AW495251 Protein, Ntrkr3 Protein, tyro10 Protein, DDR2 Protein, Tyro10 Protein, ddr2 Protein, si:ch211-193c2.1 Protein, discoidin domain receptor tyrosine kinase 2 Protein, discoidin domain receptor family, member 2 Protein, discoidin domain receptor family, member 2, like Protein, DDR2 Protein, Ddr2 Protein, ddr2l Protein
- Background
- Discoidin domain receptor (DDR) 2 is a collagen receptor that is implicated in several cancer types including breast and prostate cancers. DDR2 might be closely associated with ovarian cancer progression and metastasis. Its high expression may serve as a potential prognostic biomarker in human ovarian cancer.
- Molecular Weight
- 43.80 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q16832
- Pathways
- RTK Signaling
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