PF4V1 Protein (AA 31-104) (Fc Tag)
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- Target See all PF4V1 Proteins
- PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-104
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PF4V1 protein is labelled with Fc Tag.
- Purpose
- Human CXCL4L1 Protein
- Sequence
- Phe31-Ser104
- Characteristics
- Recombinant Human CXCL4L1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Ser104.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Platelet Factor 4 Variant 1 (PF4V1) (AA 31-104) protein (His tag)
PF4V1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Platelet Factor 4 Variant 1 (PF4V1) protein (Myc-DYKDDDDK Tag)PF4V1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))
- Alternative Name
- CXCL4L1 (PF4V1 Products)
- Synonyms
- PF4A Protein, CXCL4L1 Protein, CXCL4V1 Protein, PF4-ALT Protein, SCYB4V1 Protein, PF4V1 Protein, platelet factor 4 variant 1 Protein, PF4V1 Protein
- Background
- Platelet factor-4 (CXCL4/PF-4) was the first chemokine shown to inhibit angiogenesis. CXCL4L1/PF-4var, recently isolated from thrombin-stimulated platelets, differing from authentic CXCL4/PF-4 in three carboxy-terminally located amino acids, was found to be more potent than CXCL4/PF-4 in inhibiting angiogenesis and tumor growth. Both glycosaminoglycans (GAG) and CXCR3 are implicated in the activities of the PF-4 variants.
- Molecular Weight
- 35.01 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.
- UniProt
- P10720
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