CXCL13 Protein (AA 23-109) (His-SUMO Tag)
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- Target See all CXCL13 Proteins
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-109
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CXCL13 protein is labelled with His-SUMO Tag.
- Purpose
- Human CXCL13/BCA-1 Protein
- Sequence
- Val23-Pro109
- Characteristics
- Recombinant Human CXCL13/BCA-1 Protein is expressed from E.coli with His tag and Sumo tag at the N-Terminus.It contains Val23-Pro109.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Anti-CXCL13 Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CXCL13, His Tag with the EC50 of 0.54μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CXCL13 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 0.1M Glycine, 0.3M NaCl, 0.2M L-arginine, 10 % Glycerol ( pH 3.0).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Alternative Name
- CXCL13 (CXCL13 Products)
- Synonyms
- 4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
- Background
- Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
- Molecular Weight
- 22.9 kDa. The protein migrates to 26-28 kDa based on Tris-Bis PAGE result.
- UniProt
- O43927
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