CLEC5A Protein (AA 26-190) (Fc Tag)
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- Target See all CLEC5A Proteins
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-190
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC5A protein is labelled with Fc Tag.
- Purpose
- Mouse MDL-1/CLEC5A Protein
- Sequence
- Tyr26-Lys190
- Characteristics
- Recombinant Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Tyr26-Lys190.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC5A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Alternative Name
- MDL-1 (CLEC5A Products)
- Synonyms
- CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
- Background
- In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
- Molecular Weight
- 46.2 kDa. Due to glycosylation, the protein migrates to 64-68 kDa based on Tris-Bis PAGE result.
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