CD43 Protein (AA 20-253) (His tag)
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- Target See all CD43 (SPN) Proteins
- CD43 (SPN) (Sialophorin (SPN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-253
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD43 protein is labelled with His tag.
- Purpose
- Human CD43 Protein
- Sequence
- Ser20-Arg253
- Characteristics
- Recombinant Human CD43 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-Arg253.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Alternative Name
- CD43 (SPN Products)
- Synonyms
- CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
- Background
- CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions. The induction of acute myocarditis involves the engagement of CD43 cytoplasmic tripeptide sequence KRR to ezrin-radixin-moiesin cytoskeletal proteins.
- Molecular Weight
- 24.5 kDa. Due to glycosylation, the protein migrates to 75-120 kDa based on Tris-Bis PAGE result.
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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