CD21 Protein (AA 12-963) (His tag)
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- Target See all CD21 (CR2) Proteins
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 12-963
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD21 protein is labelled with His tag.
- Purpose
- Mouse CD21 Protein
- Sequence
- Ile12-Trp963
- Characteristics
- Recombinant Mouse CD21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile12-Trp963.
- Purity
- > 90 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CR2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- Alternative Name
- CD21 (CR2 Products)
- Synonyms
- C3DR Protein, CD21 Protein, CR Protein, CVID7 Protein, SLEB9 Protein, Cd21 Protein, cd21 Protein, CR1 Protein, CR1-L Protein, CR2 Protein, complement C3d receptor 2 Protein, complement C3b/C4b receptor 1 (Knops blood group) Protein, CR2 Protein, Cr2 Protein, CR1 Protein
- Background
- A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes.
- Molecular Weight
- 106.03 kDa. Due to glycosylation, the protein migrates to 130-160 kDa based on Tris-Bis PAGE result.
- UniProt
- P19070
- Pathways
- Complement System
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