CCL24 Protein (AA 27-119) (His tag)
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- Target See all CCL24 Proteins
- CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-119
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCL24 protein is labelled with His tag.
- Purpose
- Human CCL24 Protein
- Sequence
- Val27-Cys119
- Characteristics
- Recombinant Human CCL24 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val27-Cys119.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CCL24, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 26.9ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 100 mM L-arginine ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
- Alternative Name
- CCL24 (CCL24 Products)
- Synonyms
- Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein
- Background
- C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver.
- Molecular Weight
- 11.9 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
- UniProt
- O00175
- Pathways
- Regulation of Actin Filament Polymerization
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