PTK7 Protein (AA 39-712) (His tag)
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- Target See all PTK7 Proteins
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 39-712
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTK7 protein is labelled with His tag.
- Purpose
- Cynomolgus PTK7/CCK4 Protein
- Sequence
- Ala39-Thr712
- Characteristics
- Recombinant Cynomolgus PTK7/CCK4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala39-Thr712.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Alternative Name
- PTK7 (PTK7 Products)
- Synonyms
- PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein
- Background
- Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
- Molecular Weight
- 75.73 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5VNI5
- Pathways
- RTK Signaling, Tube Formation
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