C3 Protein (AA 23-1663) (His tag)
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- Target See all C3 Proteins
- C3 (Complement Component 3 (C3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-1663
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This C3 protein is labelled with His tag.
- Purpose
- Human Complement component 3 Protein
- Sequence
- Ser23-Asn1663
- Characteristics
- Recombinant Human Complement component 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Asn1663.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- C3 (Complement Component 3 (C3))
- Alternative Name
- Complement component 3 (C3 Products)
- Synonyms
- AHUS5 Protein, ARMD9 Protein, ASP Protein, C3a Protein, C3b Protein, CPAMD1 Protein, AI255234 Protein, HSE-MSF Protein, Plp Protein, C3 Protein, C3-1 Protein, sb:cb26 Protein, si:dkey-76b14.4 Protein, wu:fi34b03 Protein, wu:fj86e11 Protein, C3d Protein, asp Protein, cpamd1 Protein, c3 Protein, complement C3 Protein, complement component 3 Protein, complement component c3a, duplicate 1 Protein, complement component 3 L homeolog Protein, complement component C3 Protein, complement C3-like Protein, C3 Protein, c3a.1 Protein, c3.L Protein, LOC443475 Protein, c3 Protein, c3-1 Protein, LOC100060539 Protein
- Background
- Complement component 3 (C3), a pivotal molecule in the complement system, is an essential immune mediator in various diseases, including psoriasis. C3 deficiency promoted imiquimod-induced skin cell apoptosis and supported greater proportions of IFN-γ T cells in the inflamed tissues.
- Molecular Weight
- 188.52 kDa. Due to enzyme lysis and glycosylation, the protein migrates to 67-68 kDa, 110-115 kDa and 140-160 kDa based on Tris-Bis PAGE result.
- UniProt
- P01024
- Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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