B7-H6 Protein (AA 25-259) (His tag)
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- Target See all B7-H6 (NCR3LG1) Proteins
- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-259
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This B7-H6 protein is labelled with His tag.
- Purpose
- Cynomolgus B7-H6/NCR3LG1 Protein
- Sequence
- Asp25-Asp259
- Characteristics
- Recombinant Cynomolgus B7-H6/NCR3LG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp25-Asp259.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.662 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product NCR3LG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
- Alternative Name
- B7-H6 (NCR3LG1 Products)
- Synonyms
- B7-H6 Protein, B7H6 Protein, DKFZp686O24166 Protein, natural killer cell cytotoxicity receptor 3 ligand 1 Protein, NCR3LG1 Protein
- Background
- B7-H6 is a glycosylated member of the B7 family of immune co-stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
- Molecular Weight
- 27.6 kDa. Due to glycosylation, the protein migrates to 40-52 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_005578557
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