BCAM Protein (AA 26-541) (His tag)
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- Target See all BCAM Proteins
- BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-541
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCAM protein is labelled with His tag.
- Purpose
- Mouse BCAM Protein
- Sequence
- Glu26-Ala541
- Characteristics
- Recombinant Mouse BCAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu26-Ala541.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product BCAM Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
- Alternative Name
- BCAM (BCAM Products)
- Synonyms
- cd239 Protein, msk19 Protein, MGC81012 Protein, LU Protein, prr2 Protein, zgc:154034 Protein, 1200005K12Rik Protein, B-CAM Protein, Gplu Protein, Lu Protein, AU Protein, CD239 Protein, MSK19 Protein, basal cell adhesion molecule (Lutheran blood group) Protein, basal cell adhesion molecule (Lutheran blood group) L homeolog Protein, basal cell adhesion molecule Protein, bcam Protein, bcam.L Protein, BCAM Protein, Bcam Protein
- Background
- Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
- Molecular Weight
- 57.95 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9R069
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