ANGPTL2 Protein (AA 260-493) (His-Avi Tag)
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- Target See all ANGPTL2 Proteins
- ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 260-493
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL2 protein is labelled with His-Avi Tag.
- Purpose
- Human ANGPTL2/Angiopoietin-like 2 Protein
- Sequence
- Thr260-His493
- Characteristics
- Recombinant Human ANGPTL2/Angiopoietin-like 2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr260-His493.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.14μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))
- Alternative Name
- ANGPTL2 (ANGPTL2 Products)
- Synonyms
- ARP2 Protein, HARP Protein, AI593246 Protein, AW260363 Protein, Arp2 Protein, ANGPTL2 Protein, angptl2 Protein, wu:fc41g02 Protein, arp2 Protein, fbnl Protein, harp Protein, angptl2a Protein, angiopoietin like 2 Protein, angiopoietin-like 2 Protein, angiopoietin-like 2b Protein, angiopoietin like 2 L homeolog Protein, ANGPTL2 Protein, Angptl2 Protein, angptl2b Protein, angptl2 Protein, angptl2.L Protein
- Background
- Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers.
- Molecular Weight
- 30.1 kDa. Due to glycosylation, the protein migrates to 31-35 kDa based on Tris-Bis PAGE result.
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