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NKG2A & CD94 protein (Fc Tag)

Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7271623
  • Target
    NKG2A & CD94
    Protein Type
    Recombinant
    Origin
    • 8
    • 3
    • 2
    • 1
    Mouse
    Source
    • 14
    HEK-293 Cells
    Purification tag / Conjugate
    Fc Tag
    Purpose
    Mouse NKG2A&CD94 Protein, Fc Tag
    Sequence
    Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94)
    Characteristics
    Mouse NKG2A&CD94, Fc Tag (NC4-M5254) is expressed from human 293 cells (HEK293). It contains AA Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94) (Accession # Q9Z202-1 (NKG2A) & O54707-1 (CD94).
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Application Notes
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 61.3 kDa. The protein migrates as 70-80 kDa under reducing (R) condition due to glycosylation.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    NKG2A & CD94
    Alternative Name
    NKG2A&CD94
    Background
    Synonyms:NKG2A & CD94,Description:CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
    Molecular Weight
    61.3 kDa
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