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IgG Fc protein (Fc Tag)

In vivo Grade Origin: Rabbit Host: Mammalian Cells Recombinant > 95 % in vivo, IsoC
Catalog No. ABIN7211749
  • Target
    IgG Fc
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Rabbit
    Source
    • 3
    Mammalian Cells
    Purification tag / Conjugate
    Fc Tag
    Application
    In vivo Studies (in vivo), Isotype Control (IsoC)
    Purpose
    In Vivo Grade Recombinant Rabbit IgG Fc Protein
    Characteristics
    The in vivo grade recombinant rabbit IgG Fc protein (rIgG Fc, Cys 105 - Lys 323 of the constant region of the IgG heavy chain, Accession # P01870-1) was produced in mammalian cells and purified by protein A. The rIgG Fc protein includes the CH2 (114-213) and CH3 (222-323) domains of the heavy chain constant region as well as the hinge region (105-113) before the CH2 domain.
    Purification
    Protein A
    Purity
    > 95 %
    Sterility
    Sterile filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg)
    Grade
    In vivo Grade
  • Application Notes
    The recombinant rabbit IgG Fc protein and mutants can be used as the isotype control of the rIgG antibodies and the rIgG Fc fusion proteins in various in vitro and in vivo experiments.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
    Expiry Date
    3 months
  • Target
    IgG Fc
    Molecular Weight
    Predicted 24.8 kDa. Due to glycosylation, the recombinant rabbit IgG Fc protein migrates to 28-32 kDa based on the Bis-Tris PAGE result.
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