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CD52 Protein (CD52) (Biotin)

CD52 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319777
  • Target See all CD52 Proteins
    CD52
    Protein Type
    Recombinant
    Origin
    • 9
    • 1
    Human
    Source
    • 8
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD52 protein is labelled with Biotin.
    Purpose
    Recombinant Human CD52 (C-Fc-Avi) Biotinylated
    Sequence
    Gly25-Ser36
    Characteristics
    Biotinylated Recombinant Human CAMPATH-1 Antigen is produced by our Mammalian expression system and the target gene encoding Gly25-Ser36 is expressed with a Fc, Avi tag at the C-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product CD52 Protein
  • Comment

    38-50 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD52
    Alternative Name
    CD52 (CD52 Products)
    Synonyms
    CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein
    Background

    Background: CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

    Synonym: CAMPATH-1 antigen, CAMPATH-1, CD52 antigen, CD52 Molecule, CD52,  CDw52, Epididymal secretory protein E5, He5, HEL-S-171mP, Human epididymis-specific protein 5

    Molecular Weight
    30.2 kDa
    UniProt
    P31358
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