Calcineurin B Protein (CAN) (His tag)

Catalog No. ABIN7318221

Product Details

Target: Calcineurin B (CAN)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Calcineurin B protein is labelled with His tag.

Purpose: Recombinant Human Calcineurin B/CNB Protein (His Tag)

Sequence: Met 1-Val170

Characteristics: Recombinant Human Calcineurin Subunit B Type 1 is produced by our E.coli expression system and the target gene encoding Met1-Val170 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Comment:

18 kDa

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 2 mM DTT, pH 8.0 .

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Calcineurin B (CAN)

Alternative Name: Calcineurin B (CAN Products)

Synonyms: PPP3RL Protein, BcDNA:RH11383 Protein, CG4209 Protein, CNB Protein, Can Protein, CnB Protein, Dmel\\CG4209 Protein, canB-4F Protein, dCnB1 Protein, Cnb Protein, Cblp Protein, CaNB2 Protein, protein phosphatase 3 regulatory subunit B, beta Protein, Calcineurin B Protein, calcineurin B Protein, protein phosphatase 3, regulatory subunit B, beta Protein, protein phosphatase 3 regulatory subunit B, alpha Protein, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) Protein, PPP3R2 Protein, CanB Protein, Cnb Protein, Ppp3r2 Protein, PPP3R1 Protein

Background:

Background: Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B). It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.

Synonym: Calcineurin Subunit B Type 1, Protein Phosphatase 2B Regulatory Subunit 1, Protein Phosphatase 3 Regulatory Subunit B Alpha Osoform 1, PPP3R1, CNA2, CNB

Molecular Weight: 21.5 kDa

UniProt: P63098

Pathways: Cellular Glucan Metabolic Process, VEGF Signaling