Apolipoprotein C-II Protein (APOC2) (His tag)
-
- Target See all Apolipoprotein C-II (APOC2) Proteins
- Apolipoprotein C-II (APOC2)
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Apolipoprotein C-II protein is labelled with His tag.
- Purpose
- Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)
- Sequence
- Met 1-Glu82
- Characteristics
- Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product APOC2 Protein
-
-
- Comment
-
14 kDa
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mMPB,150 mM NaCL,30 % glycerol, pH 7.2.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- Apolipoprotein C-II (APOC2)
- Alternative Name
- Apolipoprotein C-II (APOC2 Products)
- Synonyms
- apoc2 Protein, apoC-II Protein, fb98g08 Protein, wu:fb52e03 Protein, wu:fb71a04 Protein, wu:fb98g08 Protein, APOC2 Protein, APO-CII Protein, APOC-II Protein, RGD1560725 Protein, APOCII Protein, Apo-CII Protein, ApoC-II Protein, apolipoprotein C-II Protein, apolipoprotein C2 Protein, apoc2 Protein, APOC2 Protein, Apoc2 Protein
- Background
-
Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
Synonym: Apolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2
- Molecular Weight
- 10.0 kDa
- UniProt
- P02655
- Pathways
- Lipid Metabolism
-