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FGL1 Protein (Biotin)

FGL1 Origin: Human Host: Human Cells Recombinant >90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7319770
  • Target See all FGL1 Proteins
    FGL1 (Fibrinogen-Like 1 (FGL1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 20
    • 4
    • 4
    • 3
    • 3
    • 1
    Human
    Source
    • 18
    • 8
    • 5
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This FGL1 protein is labelled with Biotin.
    Purpose
    Recombinant Human FGL1 (C-Fc-Avi) Biotinylated
    Sequence
    Leu23-Ile312
    Characteristics
    Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Fc, Avi tag at the C-terminus.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Mouse LAG-3-His(Cat#CK56) at 2μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi(Cat#CY19). The ED50 of Human FGL1-Avi(Cat#CY19) is 0.08ug/ml.
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  • Comment

    60 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    FGL1 (Fibrinogen-Like 1 (FGL1))
    Alternative Name
    FGL1 (FGL1 Products)
    Synonyms
    MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein
    Background

    Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

    Synonym: Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1

    Molecular Weight
    62.7 kDa
    UniProt
    Q08830
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