TNNC1 Protein
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- Target See all TNNC1 Proteins
- TNNC1 (Cardiac Troponin C (TNNC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Troponin C/TNNC1 Protein
- Sequence
- Met 1-Glu161
- Characteristics
- A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- Please contact us for more information.
- Top Product
- Discover our top product TNNC1 Protein
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Cardiac Troponin C (TNNC1) (AA 1-161) protein (GST tag)
TNNC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiac Troponin C (TNNC1) protein (DYKDDDDK Tag)TNNC1 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cardiac Troponin C (TNNC1) protein (Myc-DYKDDDDK Tag)TNNC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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20 kDa
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TNNC1 (Cardiac Troponin C (TNNC1))
- Alternative Name
- TNNC1 (TNNC1 Products)
- Synonyms
- CMD1Z Protein, CMH13 Protein, TN-C Protein, TNC Protein, TNNC Protein, cTnC Protein, tnnc1 Protein, zgc:103465 Protein, PCTNC1 Protein, cmd1z Protein, cmh13 Protein, tnc Protein, tnnc Protein, MGC80066 Protein, TNNC1 Protein, AI874626 Protein, TnC Protein, cTnI Protein, tncc Protein, Tncc Protein, stnnc Protein, zgc:86932 Protein, troponin C1, slow skeletal and cardiac type Protein, troponin C type 1a (slow) Protein, troponin C type 1 (slow) L homeolog Protein, cardiac troponin C Protein, troponin C, cardiac/slow skeletal Protein, troponin C type 1b (slow) Protein, TNNC1 Protein, tnnc1a Protein, tnnc1.L Protein, tnnc1 Protein, Tnnc1 Protein, tnnc1b Protein
- Background
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Background: Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC
- Molecular Weight
- 18.4 kDa
- NCBI Accession
- NP_003271
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