TGFB1 Protein (Biotin)

Catalog No. ABIN7319931

Product Details

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This TGFB1 protein is labelled with Biotin.

Purpose: Recombinant Human Transforming Growth Factor Beta-1/TGFB1 Biotinylated

Sequence: Ala279-Ser390

Characteristics: Biotinylated Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed with a Avi tag at the N-terminus.

Purity: >95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Comment:

13 kDa

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine-HCl, 150 mM NaCl, pH 2.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Alternative Name: TGFB1 (TGFB1 Products)

Synonyms: CED Protein, DPD1 Protein, LAP Protein, TGFB Protein, TGFbeta Protein, TGF-beta Protein, TGF-BETA-1 Protein, TGF-beta5 Protein, ced Protein, dpd1 Protein, lap Protein, tgf-beta Protein, tgfb Protein, tgfb5 Protein, tgfbeta Protein, TGF-beta1 Protein, TGFbeta1 Protein, Tgfb Protein, Tgfb-1 Protein, ai39657 Protein, tgfb1 Protein, wu:fb13a07 Protein, xx:ai39657 Protein, TGFB1 Protein, csd Protein, cdb1 Protein, cdg2 Protein, csd1 Protein, csd2 Protein, csd3 Protein, ebmd Protein, lcd1 Protein, bigh3 Protein, cdgg1 Protein, betaig-h3 Protein, TGFB4 Protein, transforming growth factor beta 1 Protein, transforming growth factor beta-1 Protein, transforming growth factor beta 1 L homeolog Protein, transforming growth factor, beta 1 Protein, transforming growth factor, beta 1a Protein, transforming growth factor beta induced L homeolog Protein, TGFB1 Protein, Tgfb1 Protein, tgfb1.L Protein, tgfb1a Protein, tgfbi.L Protein

Background:

Background: Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Synonym: Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB

Molecular Weight: 14.6 kDa

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints