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IL-33 Protein (His tag)

IL33 Origin: Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320998
  • Target See all IL-33 (IL33) Proteins
    IL-33 (IL33) (Interleukin 33 (IL33))
    Protein Type
    Recombinant
    Origin
    • 18
    • 14
    • 4
    • 2
    • 1
    • 1
    Rhesus Monkey
    Source
    • 24
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL-33 protein is labelled with His tag.
    Purpose
    Recombinant Rhesus macaque IL-33/Interleukin-33 Protein (His Tag)
    Sequence
    Ser112-Ile270
    Characteristics
    Recombinant Rhesus macaque Interleukin 33 is produced by our E.coli expression system and the target gene encoding Ser112-Ile270 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL33 Protein
  • Comment

    21 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Alternative Name
    IL-33/Interleukin-33 (IL33 Products)
    Synonyms
    IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
    Background

    Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

    Synonym: Interleukin-33, IL-33, Interleukin-1 Family Member 11, IL-1F11, Nuclear Factor From High Endothelial Venules, NF-HEV, IL33, C9orf26, IL1F11, NFHEV

    Molecular Weight
    20.3 kDa
    UniProt
    F7DLG4
    Pathways
    Production of Molecular Mediator of Immune Response
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