XPNPEP3 Protein (His tag)
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- Target See all XPNPEP3 Proteins
- XPNPEP3 (X-Prolyl Aminopeptidase (Aminopeptidase P) 3, Putative (XPNPEP3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This XPNPEP3 protein is labelled with His tag.
- Purpose
- Recombinant Human XPNPEP3 Protein (His Tag)
- Sequence
- Met 1-Ser507
- Characteristics
- Recombinant Human Probable Xaa-Pro Aminopeptidase 3 is produced by our E.coli expression system and the target gene encoding Met1-Ser507 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product XPNPEP3 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 25 mM Tris, 1 mM DTT, pH 7.3.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- XPNPEP3 (X-Prolyl Aminopeptidase (Aminopeptidase P) 3, Putative (XPNPEP3))
- Alternative Name
- XPNPEP3 (XPNPEP3 Products)
- Synonyms
- APP3 Protein, NPHPL1 Protein, E430012M05Rik Protein, X-prolyl aminopeptidase 3 Protein, X-prolyl aminopeptidase 3, mitochondrial Protein, XPNPEP3 Protein, xpnpep3 Protein, Xpnpep3 Protein
- Background
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Background: Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
Synonym: Probable Xaa-Pro Aminopeptidase 3, X-Pro Aminopeptidase 3, Aminopeptidase P3, APP3, XPNPEP3
- Molecular Weight
- 60.2 kDa
- UniProt
- Q9NQH7
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