VISTA Protein (His tag)
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- Target See all VISTA Proteins
- VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
- Protein Type
- Recombinant
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Origin
- Cynomolgus
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Source
- Human Cells
- Purification tag / Conjugate
- This VISTA protein is labelled with His tag.
- Purpose
- Recombinant Cynomolgus VSIR Protein (His Tag)
- Sequence
- Phe33-Ala194
- Characteristics
- Recombinant Cynomolgus VSIR is produced by our Mammalian expression system and the target gene encoding Phe33-Ala194 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) (AA 1-311) protein (GST tag)
VISTA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) protein (Myc-DYKDDDDK Tag)VISTA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) protein (DYKDDDDK-His Tag)VISTA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
- Alternative Name
- VSIR (VISTA Products)
- Synonyms
- MGC112715 Protein, MGC151567 Protein, B7-H5 Protein, B7H5 Protein, GI24 Protein, PP2135 Protein, SISP1 Protein, Dies1 Protein, VISTA Protein, V-set immunoregulatory receptor Protein, vsir Protein, Vsir Protein, VSIR Protein
- Background
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Background: platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.
Synonym: Platelet receptor Gi24,Stress-induced secreted protein-1,Sisp-1,C10orf54,SISP1
- Molecular Weight
- 19.2 kDa
- UniProt
- A0A2K5UV12
- Pathways
- Cancer Immune Checkpoints
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