VSTM1 Protein (His tag)
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- Target See all VSTM1 Proteins
- VSTM1 (V-Set and Transmembrane Domain Containing 1 (VSTM1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This VSTM1 protein is labelled with His tag.
- Purpose
- Recombinant Human VSTM1 Protein (His Tag)
- Sequence
- Tyr17-Thr135
- Characteristics
- Recombinant Human V-set and Transmembrane Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr17-Thr135 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product VSTM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- VSTM1 (V-Set and Transmembrane Domain Containing 1 (VSTM1))
- Alternative Name
- VSTM1 (VSTM1 Products)
- Synonyms
- SIRL1 Protein, UNQ3033 Protein, V-set and transmembrane domain containing 1 Protein, VSTM1 Protein
- Background
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Background: V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
Synonym: V-set and transmembrane domain-containing protein 1,SIRL-1,Signal inhibitory receptor on leukocytes-1,VSTM1
- Molecular Weight
- 14.6 kDa
- UniProt
- Q6UX27
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