UROD Protein (His tag)
-
- Target See all UROD Proteins
- UROD (Uroporphyrinogen Decarboxylase (UROD))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UROD protein is labelled with His tag.
- Purpose
- Recombinant Human UROD Protein (His Tag)
- Sequence
- Met 1-Asn367
- Characteristics
- Recombinant Human Uroporphyrinogen Decarboxylase is produced by our E.coli expression system and the target gene encoding Met1-Asn367 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UROD Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- UROD (Uroporphyrinogen Decarboxylase (UROD))
- Alternative Name
- UROD (UROD Products)
- Synonyms
- UROD Protein, pct Protein, wu:fc43e09 Protein, PCT Protein, UPD Protein, AI323803 Protein, Uro-d Protein, porphyrinogen carboxy-lyase Protein, uroporphyrinogen decarboxylase Protein, Uroporphyrinogen decarboxylase UroD Protein, Uroporphyrinogen decarboxylase Protein, UROD Protein, urod Protein, hemE Protein, uroD Protein, Cpin_6502 Protein, Rmar_1187 Protein, LOC5568261 Protein, Mrub_1403 Protein, Arnit_2230 Protein, Ndas_2830 Protein, Mesil_2989 Protein, Trad_0222 Protein, Weevi_0432 Protein, Hipma_1229 Protein, Fluta_0529 Protein, Marky_1143 Protein, Halhy_5610 Protein, Mesop_0899 Protein, Ccan_20670 Protein, Urod Protein
- Background
-
Background: Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).
Synonym: Uroporphyrinogen Decarboxylase, UPD, URO-D, UROD
- Molecular Weight
- 43.0 kDa
- UniProt
- P06132
-