ULBP2 Protein (Fc Tag)
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- Target See all ULBP2 Proteins
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ULBP2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)(Active)
- Sequence
- Gly26-Ser217
- Characteristics
- Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2 is produced by our Mammalian expression system and the target gene encoding Gly26-Ser217 is expressed with a Fc tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human NKG2DL2-Fc at 8μg/ml(100 μl/well) can bind Human NKG2D-His(Cat: PKSH033409). The ED50 of Human NKG2DL2-Fc is 10.32 ug/ml .
- Top Product
- Discover our top product ULBP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Alternative Name
- ULBP2/N2DL-2 (ULBP2 Products)
- Synonyms
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- Background
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Background: NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.
Synonym: NKG2D Ligand 2, N2DL-2, NKG2DL2, ALCAN-Alpha, Retinoic Acid Early Transcript 1H, UL16-Binding Protein 2, ULBP2, N2DL2, RAET1H
- Molecular Weight
- 51.4 kDa
- UniProt
- Q9BZM5
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