UBE2A Protein (GST-His-Tag)
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- Target See all UBE2A (ube2a) Proteins
- UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2A protein is labelled with GST-His-Tag.
- Purpose
- Recombinant Human UBE2A Protein (GST & His Tag)
- Sequence
- Met 1-Cys152
- Characteristics
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 A is produced by our E.coli expression system and the target gene encoding Met1-Cys152 is expressed with a GST, 6His tag at the N-terminus.
- Purity
- > 80 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ube2a Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))
- Alternative Name
- UBE2A (ube2a Products)
- Synonyms
- BHR6A Protein, HR6A Protein, hhr6a Protein, rad6a Protein, ubc2 Protein, mp:zf637-2-000771 Protein, si:bz46j2.4 Protein, wu:fa01h11 Protein, HHR6A Protein, MRXS30 Protein, MRXSN Protein, RAD6A Protein, UBC2 Protein, Mhr6a Protein, ubiquitin conjugating enzyme E2 A Protein, ubiquitin conjugating enzyme E2 A L homeolog Protein, ubiquitin-conjugating enzyme E2A (RAD6 homolog) Protein, ubiquitin-conjugating enzyme E2A Protein, UBE2A Protein, ube2a.L Protein, ube2a Protein, Ube2a Protein
- Background
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Background: Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.
Synonym: Ubiquitin-Conjugating Enzyme E2 A, RAD6 Homolog A, HR6A, hHR6A, Ubiquitin Carrier Protein A, Ubiquitin-Protein Ligase A, UBE2A, RAD6A
- Molecular Weight
- 49.0 kDa
- UniProt
- P49459
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