WARS Protein (His tag)

Catalog No. ABIN7319122

Product Details

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This WARS protein is labelled with His tag.

Purpose: Recombinant Human WARS/TrpRS Protein (His Tag)

Sequence: Met 1-Gln471

Characteristics: Recombinant Human Tryptophan--tRNA ligase, cytoplasmic is produced by our E.coli expression system and the target gene encoding Met1-Gln471 is expressed with a 6His tag at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS/TrpRS (WARS Products)

Background:

Background: There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.

Synonym: WARS also known as Tryptophanyl-tRNA synthetase, Interferon-induced protein 53.

Molecular Weight: 55.3 kDa

UniProt: P23381