TPSB2 Protein (His tag)
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- Target See all TPSB2 Proteins
- TPSB2 (Tryptase beta 2 (TPSB2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This TPSB2 protein is labelled with His tag.
- Purpose
- Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)
- Sequence
- Ala19-Pro275
- Characteristics
- Recombinant Human Tryptase beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TPSB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TPSB2 (Tryptase beta 2 (TPSB2))
- Alternative Name
- Tryptase beta-2/TPSB2 (TPSB2 Products)
- Synonyms
- TPS2 Protein, tryptaseB Protein, tryptaseC Protein, Mcpt6 Protein, tryptase beta 2 (gene/pseudogene) Protein, tryptase beta 2 Protein, TPSB2 Protein, Tpsb2 Protein
- Background
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Background: Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Synonym: Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2
- Molecular Weight
- 29.6 kDa
- UniProt
- P20231
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