CD300LG Protein

Catalog No. ABIN7317256

Product Details

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purpose: Recombinant Human CLM-9/TREM4 Protein

Sequence: Met 1-Arg247

Characteristics: A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Alternative Name: CLM-9/TREM4 (TREM4 Products)

Synonyms: RGD1311074 Protein, 2310016B05Rik Protein, Clm9 Protein, D11Ertd736e Protein, CLM-9 Protein, CLM9 Protein, NEPMUCIN Protein, TREM-4 Protein, TREM4 Protein, Cd300 molecule-like family member G Protein, CD300 molecule like family member G Protein, CD300 molecule like family member g Protein, triggering receptor expressed on myeloid cells 4 Protein, Cd300lg Protein, CD300LG Protein, Trem4 Protein

Background:

Background: CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

Synonym: CMRF35-Like Molecule 9, CLM-9, CD300 Antigen-Like Family Member G, Triggering Receptor Expressed on Myeloid Cells 4, TREM-4, CD300g, CD300LG, CLM9, TREM4,NEPMUCIN

Molecular Weight: 25.5 kDa