TSPAN1 Protein (Fc Tag)
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- Target See all TSPAN1 Proteins
- TSPAN1 (Tetraspanin 1 (TSPAN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TSPAN1 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag)
- Sequence
- Tyr110-Asn211
- Characteristics
- A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TSPAN1 Protein
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Tetraspanin 1 (TSPAN1) (AA 110-211) protein (GST tag)
TSPAN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tetraspanin 1 (TSPAN1) (AA 1-241) protein (GST tag)TSPAN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TSPAN1 (Tetraspanin 1 (TSPAN1))
- Alternative Name
- TSPAN1 (TSPAN1 Products)
- Synonyms
- TSPAN1 Protein, 9030418M05Rik Protein, NET1 Protein, TM4C Protein, TM4SF Protein, tetraspanin 1 Protein, tetraspanin 1 L homeolog Protein, TSPAN1 Protein, tspan1.L Protein, Tspan1 Protein
- Background
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Background: TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone, in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.
Synonym: NET1,TM4C,TM4SF,TSPAN1
- Molecular Weight
- 39.1 kDa
- UniProt
- O60635
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