SENP2 Protein (SUMO Tag,His tag)
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- Target See all SENP2 Proteins
- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SENP2 protein is labelled with SUMO Tag,His tag.
- Purpose
- Recombinant Human SENP2 Protein (His Tag, SUMO Tag)
- Sequence
- Asp363-Leu589
- Characteristics
- Recombinant Human Sentrin-specific protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SENP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES,5 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
- Alternative Name
- SENP2 (SENP2 Products)
- Synonyms
- 2310007L05Rik Protein, 4930538C18Rik Protein, AI646780 Protein, AW554757 Protein, Smt3ip2 Protein, SuPr-1 Protein, mKIAA1331 Protein, AXAM2 Protein, SMT3IP2 Protein, Axam Protein, SUMO/sentrin specific peptidase 2 Protein, SUMO1/sentrin/SMT3 specific peptidase 2 Protein, Sumo1/sentrin/SMT3 specific peptidase 2 Protein, Senp2 Protein, SENP2 Protein
- Background
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Background: SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Synonym: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.
- Molecular Weight
- 26.8 kDa
- UniProt
- Q9HC62
- Pathways
- Chromatin Binding
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