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Stathmin 1 Protein (STMN1) (His tag)

STMN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319053
  • Target See all Stathmin 1 (STMN1) Proteins
    Stathmin 1 (STMN1)
    Protein Type
    Recombinant
    Origin
    • 9
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 3
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Stathmin 1 protein is labelled with His tag.
    Purpose
    Recombinant Human STMN1 Protein (His Tag)
    Sequence
    Ala2-Asp149
    Characteristics
    Recombinant Human Stathmin is produced by our E.coli expression system and the target gene encoding Ala2-Asp149 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product STMN1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Stathmin 1 (STMN1)
    Alternative Name
    STMN1 (STMN1 Products)
    Background

    Background: Stathmin (STMN1) is a ubiquitous cytosolic phosphoprotein which belongs to the Stathmin family. STMN1 is expressed in many tissues, with the highest expression in the brain, spinal cord, and cerebellum. It can also be expressed in the colon, ovary, placenta, uterus, and trachea. STMN1 participates in the regulation of the microtubule filament structure by destabilizing microtubules. STMN1 promotes the disassembly of microtubules and prevents assembly. STMN1 is involved in the control of the learned and innate fear. STMN1 is an intracellular relay integrating regulatory signals of the cellular environment and as an Oncoprotein in regulation of the cell cycle. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Mutation in STMN1 effects cell homeostasis that may lead to tumorigenicity.

    Synonym: Stathmin, Leukemia-Associated Phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17, STMN1, C1orf215, LAP18, OP18

    Molecular Weight
    18.4 kDa
    UniProt
    P16949
    Pathways
    MAPK Signaling, Microtubule Dynamics
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