Stanniocalcin 1 Protein (STC1) (His tag)
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- Target See all Stanniocalcin 1 (STC1) Proteins
- Stanniocalcin 1 (STC1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Stanniocalcin 1 protein is labelled with His tag.
- Purpose
- Recombinant Human Stanniocalcin 1/STC-1 (C-6His)
- Sequence
- Thr18-Ala247
- Characteristics
- Recombinant Human Stanniocalcin 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product STC1 Protein
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Stanniocalcin 1 (STC1) (AA 39-247) protein (His tag)
STC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Stanniocalcin 1 (STC1) (AA 141-247) protein (GST tag)STC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Stanniocalcin 1 (STC1) (AA 39-247), (partial) protein (GST tag)STC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Stanniocalcin 1 (STC1) protein (DYKDDDDK-His Tag)STC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Stanniocalcin 1 (STC1)
- Alternative Name
- Stanniocalcin 1/STC-1 (STC1 Products)
- Synonyms
- STC Protein, Stc Protein, stc1 Protein, MGC82280 Protein, STC1 Protein, zgc:153307 Protein, LOC777959 Protein, stanniocalcin 1 Protein, stanniocalcin 1 L homeolog Protein, stanniocalcin 1 S homeolog Protein, STC1 Protein, Stc1 Protein, stc1.L Protein, stc1.S Protein, stc1 Protein, LOC777959 Protein
- Background
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Background: Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation.
Synonym: Stanniocalcin 1, stanniocalcin-1, STC1, STC-1, STCSTC-1
- Molecular Weight
- 26.9 kDa
- UniProt
- P52823
- Pathways
- Hormone Activity
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