SRGN Protein (His tag)

Catalog No. ABIN7317218

Product Details

Target: SRGN (serglycin (SRGN))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SRGN protein is labelled with His tag.

Purpose: Recombinant Human Serglycin/SRGN Protein (His Tag)

Sequence: Met 1-Leu158

Characteristics: A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SRGN (serglycin (SRGN))

Alternative Name: Serglycin/SRGN (SRGN Products)

Synonyms: PPG Protein, PRG Protein, PRG1 Protein, Prg Protein, Prg1 Protein, Sgc Protein, Pgsg Protein, serglycin Protein, SRGN Protein, Srgn Protein

Background:

Background: SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

Synonym: PPG,PRG,PRG1

Molecular Weight: 16.1 kDa

Pathways: Maintenance of Protein Location