SEMA4C Protein (Fc Tag)
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- Target See all SEMA4C Proteins
- SEMA4C (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4C (SEMA4C))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This SEMA4C protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse Semaphorin-4C/SEMA4C Protein (Fc Tag)
- Sequence
- Ala21-Gly664
- Characteristics
- Recombinant Mouse Semaphorin 4C is produced by our Mammalian expression system and the target gene encoding Ala21-Gly664 is expressed with a Fc tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SEMA4C Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SEMA4C (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4C (SEMA4C))
- Alternative Name
- Semaphorin-4C/SEMA4C (SEMA4C Products)
- Synonyms
- M-SEMA-F Protein, SEMACL1 Protein, SEMAF Protein, SEMAI Protein, AI426163 Protein, Semacl1 Protein, Semaf Protein, Semai Protein, mKIAA1739 Protein, RGD1562837 Protein, semaphorin 4C Protein, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Protein, SEMA4C Protein, Sema4c Protein
- Background
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Background: Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Synonym: Semaphorin-4C,Semaphorin I,S4c, Semacl1, Semai,Sema I,Semaphorin-C-like 1,M-Sema F,Sema4c
- Molecular Weight
- 99.3 kDa
- UniProt
- Q64151
- Pathways
- Tube Formation
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