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SHPK Protein (His tag)

SHPK Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318998
  • Target See all SHPK Proteins
    SHPK (Sedoheptulokinase (SHPK))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This SHPK protein is labelled with His tag.
    Purpose
    Recombinant Human Sedoheptulokinase/SHPK Protein (His Tag)
    Sequence
    Met 1-Ser478
    Characteristics
    Recombinant Human Sedoheptulokinase is produced by our Mammalian expression system and the target gene encoding Met1-Ser478 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SHPK Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    SHPK (Sedoheptulokinase (SHPK))
    Alternative Name
    Sedoheptulokinase/SHPK (SHPK Products)
    Synonyms
    SHPK Protein, CARKL Protein, carkl Protein, MGC154818 Protein, SHK Protein, 4930431K22Rik Protein, AI194947 Protein, AW260459 Protein, Carkl Protein, sedoheptulokinase Protein, sedoheptulokinase S homeolog Protein, Sedoheptulokinase Protein, SHPK Protein, shpk.S Protein, Plabr_2171 Protein, shpk Protein, Shpk Protein
    Background

    Background: Sedoheptulokinase (SHPK) belongs to the FGGY kinase family, and is mainly located in cytoplasm. SHPK is strongly expressed in liver, kidney and pancreas. It is expressed at lower levels in placenta and heart, and very weakly expressed in lung and brain. SHPK catalyzes the chemical reaction: ATP + sedoheptulose = ADP + sedoheptulose 7-phosphatecan, It can transform sedoheptulose to sedoheptulose 7-phosphate in the condition of ATP, and acts as a modulator of macrophage activation through control of glucose metabolism. In addition, It also can be down-regulated by LPS.

    Synonym: Sedoheptulokinase,SHK,Carbohydrate kinase-like protein,SHPK,CARKL

    Molecular Weight
    52.5 kDa
    UniProt
    Q9UHJ6
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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