SCGB3A2 Protein

Catalog No. ABIN7319165

Product Details

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human UGRP1 Protein

Sequence: Phe22-Val93

Characteristics: Recombinant Human Uteroglobin-Related Protein 1 is produced by our E.coli expression system and the target gene encoding Phe22-Val93 is expressed.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Alternative Name: UGRP1 (SCGB3A2 Products)

Synonyms: SCGB3A2 Protein, LU103 Protein, PNSP1 Protein, UGRP1 Protein, pnSP-1 Protein, LuLeu1 Protein, Pnsp1 Protein, Utgrp1 Protein, secretoglobin family 3A member 2 Protein, secretoglobin, family 3A, member 2 Protein, SCGB3A2 Protein, Scgb3a2 Protein

Background:

Background: Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.

Synonym: Secretoglobin Family 3A Member 2, Pneumo Secretory Protein 1, PnSP-1, Uteroglobin-Related Protein 1, SCGB3A2, PNSP1, UGRP1

Molecular Weight: 7.9 kDa

UniProt: Q96PL1