RPS19 Protein

Catalog No. ABIN7318112

Product Details

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human RPS19 Protein

Sequence: Pro2-His145

Characteristics: Recombinant Human 40S Ribosomal Protein S19 is produced by our E.coli expression system and the target gene encoding Pro2-His145 is expressed.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Alternative Name: RPS19 (RPS19 Products)

Synonyms: DBA Protein, DBA1 Protein, S19 Protein, Dsk3 Protein, 30S ribosomal protein S19 Protein, 40S ribosomal protein S19 Protein, ribosomal protein S19 Protein, rps19 Protein, rps-19 Protein, RPS19 Protein, Rps19 Protein

Background:

Background: 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.

Synonym: 40S Ribosomal Protein S19, RPS19

Molecular Weight: 16.1 kDa

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly