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RNASET2 Protein (His tag)

RNASET2 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 98 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7197719
  • Target See all RNASET2 Proteins
    RNASET2 (Ribonuclease T2 (RNASET2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 2
    • 1
    Human
    Source
    • 6
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This RNASET2 protein is labelled with His tag.
    Purpose
    Recombinant Human RNASET2 Protein (Baculovirus, His Tag)
    Sequence
    Met 1-His 256
    Characteristics
    A DNA sequence encoding the human RNASET2 isoform 1 (O00584-1) (Met 1-His 256) was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 98 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product RNASET2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    RNASET2 (Ribonuclease T2 (RNASET2))
    Alternative Name
    RNASET2 (RNASET2 Products)
    Synonyms
    RNASE6PL Protein, bA514O12.3 Protein, MGC83874 Protein, MGC145364 Protein, dre2 Protein, wu:fc10c06 Protein, zgc:113369 Protein, ribonuclease T2 Protein, ribonuclease T2 L homeolog Protein, ribonuclease t2 Protein, RNASET2 Protein, Rnaset2 Protein, rnaset2.L Protein, rnaset2 Protein, TM1040_2631 Protein, RPE_1409 Protein, Bind_1696 Protein, Dd586_2225 Protein, Nhal_0810 Protein, Snov_2442 Protein, Fbal_2689 Protein, Nitsa_0808 Protein, Mesop_3495 Protein
    Background

    Background: RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly. An infantile-onset syndrome of cerebral leukoencephalopathy. Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment. The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications.

    Synonym: Ribonuclease T2,3.1.27.-,Ribonuclease 6,RNASE6PL

    Molecular Weight
    28.5 kDa
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