Proteoglycan 3 Protein (PRG3) (His tag)
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- Target See all Proteoglycan 3 (PRG3) Proteins
- Proteoglycan 3 (PRG3)
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Proteoglycan 3 protein is labelled with His tag.
- Purpose
- Recombinant Human Proteoglycan 3/PRG3 Protein (His Tag)
- Sequence
- Leu18-Phe225
- Characteristics
- Recombinant Human Proteoglycan 3 is produced by our Mammalian expression system and the target gene encoding Leu18-Phe225 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRG3 Protein
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Proteoglycan 3 (PRG3) protein (Myc-DYKDDDDK Tag)
PRG3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Proteoglycan 3 (PRG3)
- Alternative Name
- Proteoglycan 3/PRG3 (PRG3 Products)
- Synonyms
- MBP2 Protein, MBPH Protein, proteoglycan 3, pro eosinophil major basic protein 2 Protein, proteoglycan 3 Protein, PRG3 Protein, Prg3 Protein
- Background
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Background: Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.
Synonym: Proteoglycan 3, Eosinophil Major Basic Protein Homolog, Prepro-Major Basic Protein Homolog, Prepro-MBPH, PRG3, MBPH
- Molecular Weight
- 24.6 kDa
- UniProt
- Q9Y2Y8
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